A reference directory of HHS/SAMHSA-certified labs, drug testing platforms, clearinghouses, and point-of-care suppliers for DOT and non-DOT workplace testing programs.
Two separate categories — read the distinction before choosing a laboratory
A DOT urine specimen may go only to a laboratory appearing on the current HHS-certified laboratory list (§40.81). That list is reissued by SAMHSA monthly, and laboratories are added to and removed from it, so certification is a status to check at the moment of use — not a fixed attribute of a company.
This page deliberately does not reproduce that list. Any copy of it here would be out of date within the month, and a stale copy is worse than none. The official list is the only authority for DOT eligibility:
Laboratories commonly encountered in workplace testing, listed for reference and for non-DOT work. Appearing here is not a representation that a laboratory is currently HHS-certified for DOT urine testing. Several of these are known for specialty or non-regulated testing. Before sending any DOT specimen, check the laboratory against Category 1 above.
One of the two largest clinical lab networks in the US. Widely integrated with most TPA platforms and clearinghouses. Serves both regulated and non-regulated employer programmes.
The other major national lab network. Broad collection site infrastructure, deep employer relationships, and strong MRO services integration. Widely accepted by TPAs and clearinghouses.
Known for specialty testing including meconium, EtG (alcohol biomarker), hair, and oral fluid in addition to standard urine panels. Listed here for reference and non-DOT work — check the current HHS list before any DOT specimen.
Competitive turnaround times and employer-focused services. Strong alternative to the two major networks for TPAs looking for independent lab partnerships.
Offers urine, oral fluid, and hair testing with strong TPA and employer partnership programs. Known for relationship-driven service and fast reporting.
California-based independent lab focused on employer and occupational health programmes. Listed here for reference and non-DOT work — check the current HHS list before any DOT specimen.
Growing national lab presence with a focus on court-ordered monitoring and substance abuse programs in addition to employer workplace testing.
Part of Abbott Laboratories. High-volume lab capacity with national reach. Integrated with Abbott's broader point-of-care and workplace testing ecosystem.
TPA platforms that connect collectors, labs, MROs, and employers
The leading electronic CCF (eCCF) platform connecting collectors, labs, MROs, and TPAs across 3,500+ collection sites. Supports urine, hair, oral fluid, BAT, and point-of-care testing. Most large drug testing programs run through FormFox.
One of the largest TPAs in the country, serving 55,000+ companies. Manages millions of tests annually. Their DISA 360 platform includes FMCSA Clearinghouse reporting, compliance tracking, and employer program management.
Technology-driven TPA platform for specimen collection, management, and results reporting. Connects employers with collection sites and labs through a centralized dashboard.
Employment screening company offering drug testing alongside background checks, verifications, and compliance tools. Well-established with large national employers.
Background screening and drug testing provider serving mid-to-large employers. Offers program management and integration with HR platforms.
TPA offering drug testing program management, eCCF technology, lab navigation, and compliance support for employers and collectors nationwide.
TPA platform focused on employer drug and alcohol testing program compliance, random pool management, and reporting.
Occupational health clinics offering on-site collections, physicals, and employer services nationwide. A strong referral partner for collectors who don't yet have a clinic presence.
Employment screening platform offering drug testing, background checks, and I-9 verification. Primarily serves large enterprise employers.
For non-DOT onsite testing — most TPAs use FUO devices (no CLIA needed). A CLIA Certificate of Waiver is only required when reading FDA-cleared / CLIA-Waived devices for clinical purposes.
None of the devices in this section can be used as a DOT drug test. §40.81 requires every DOT drug specimen to be tested by an HHS-certified laboratory, so an instant/point-of-collection result never satisfies a DOT testing requirement no matter what the supplier’s marketing says. Where a vendor below is described as serving “DOT”, that refers to their collection supplies or their lab-based service line — not to the rapid devices.
5-minute rapid workplace tests with paperless administration and expanded panels, plus lab-based DOT service lines. Part of the Abbott Laboratories family. The rapid devices themselves are non-DOT only.
Bulk wholesale supplier of test cups, dip cards, saliva strips, and urine test panels. Collection supplies may support DOT programs; the rapid/point-of-collection testing devices are for non-DOT testing only. Competitive pricing for high-volume buyers.
CLIA-waived, FDA 510(k) cleared urine drug screen cups and dip cards. Available in 5, 6, 10, and 12-panel options for employer and healthcare use.
20+ years in the industry. Offers rapid urine, oral fluid, and hair test products with 5—10 minute results for workplace and healthcare settings.
Point-of-care test products integrated with lab confirmation services. Useful for non-DOT programs that want rapid results with lab backup for positive screens.
Once you've picked your lab and clearinghouse partners, get your collectors DOT-qualified, your business accredited, and your site listed.